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Nanotechnology will have future medical applications leading to the emergence of nanomedicine and nanodentistry. Nanodentistry will make it possible to maintain a near perfect oral health through the use of nanomaterials, biotechnology, including tissue engineering and nanorobotics. The nanorobotic functions may be controlled by an onboard nanocomputer that executes preprogrammed instructions in response to local sensor stimuli. The outline of this course is to familiarize the students with the current and prospective applications of nanotechnology in Dentistry.